Human chorionic gonadotrophin (b-hCG)

Immunohistochemical expression

Expressed by syncytiotrophoblast but not markedly by other forms of trophoblast or their tumour1.

Diagnostic utility


1Singer, G., R. J. Kurman, et al. (2002). "HLA-G immunoreactivity is specific for intermediate trophoblast in gestational trophoblastic disease and can serve as a useful marker in differential diagnosis." Am J Surg Pathol 26(7): 914-20.


©SMUHT/PW Bishop