CDw75

CDw75 is a sialylated carbohydrate epitope. CDw75 is detected in paraffin-embedded tissues by LN12.

Immunohistochemical expression

 

 

Malignant pleural epithelioid mesothelioma

10/213

 

Malignant peritoneal epithelioid mesothelioma

8/203

Peripheral pulmonary adenocarcinoma involving pleura

21/233

Serous surface papillary adenocarcinoma of peritoneum

10/103

Breast carcinoma metastatic to pleura

6/103

   

 

Diagnostic utility

References

1 GO Elpek et al. Clinicopathologic evaluation of CDw75 antigen expression in patients with gastric carcinoma. J Pathol 2001; 193: 169-174.

2 Leong A S-Y, Cooper K and Leong FJ W-M. Manual of diagnostic antibodies for immunohistology. 2nd edition, 2003

3 Wick MR, Mills SE,Swanson PE Expression of "myelomonocytic" antigens in mesotheliomas and adenocarcinomas involving the serosal surfaces. Am J Clin Pathol 1990; 94:18-26

This page last revised 19.8.2005.

 

©SMUHT/PW Bishop