Synovial sarcoma vs mesothelioma

Synovial sarcoma

Mesothelioma

biphasic

monophasic

poorly differentiated

epithelioid

sarcomatoid

Calretinin

29/41(epithelial component positive in 14 cases, of which 5 showed staining of >10% of cells. spindle cell component positive in 24 cases, extensive in some, both cytoplasmic and nuclear.)

23/44(more than 10% of cells positive in 17 cases.

10/18(more than 10% of cells positive in 6 cases.

23/23(extensive positivity)

7/7(focal to extensive positivity)

HBME-1

28/28(cytoplasmic and membrane, extensive in most cases)

8/20(mainly focal

2/14

20/23(membrane positivity)

0/7

BerEP4

27/30(extensive staining of epithelial component)

2/28(focal reactivity)

1/16(focal reactivity)

3/23(focal reactivity)

0/7

CD15

3/32(focal reactivity)

1/33(focal reactivity)

1/17(focal reactivity)

5/17(focal reactivity)

4/7

CD141

7/20(focal reactivity only of spindle cells)

11/33(focal reactivity)

1/11

20/21

5/7

CK5/6

22/29

12/40(focal reactivity)

3/17(focal reactivity)

21/23

1/7

CK7

41/41(epithelial component)

32/41(focal reactivity)

9/18(focal reactivity)

23/23

7/7

CK14

29/44(epithelial component)

11/40(focal reactivity)

1/12(focal reactivity)

12/23(focal reactivity)

4/7(focal reactivity)

CK19

41/41(epithelial component)

25/41(focal reactivity)

11/18(focal reactivity)

23/23

7/7

WT1

0/18

0/31

0/11

12/17

0/7