Testicular seminoma

Cam5.2

19/641

AE1/AE3

23/641, 0/184,17/415, 9/216, 5/397, 9/268

WSK

23/641

HMWK

0/641

CK7

26/641

CK20

0/641

EMA

1/641, 0/72, 0/397

PLAP

64/641, 6/72, 199/1993

CEA

0/72

HCG

0/72

AFP

0/72

vimentin

0/7

CD15

0/72

CD30

4/641, 0/72

NSE

7/72

Differential diagnosis

References

1 Cheville, J. C., Rao, S., Iczkowski, K. A., Lohse, C. M., Pankratz, V. S. Cytokeratin expression in seminoma of the human testis. Am J Clin Pathol 2000; 13: 583-8.

2 Ro J et al. Nonseminomatous germ cell tumors of the testis: an immunohistochemical study of 46 cases. Lab Invest 1991;64:50A.

3 Tissue array of a historical archive: the British Testicular Tumour Panel Series. Pathological Society January 2005, abstract 58.

4 Battifora H, Sheibani K, Tubbs RR, et al. Antikeratin antibodies in tumor diagnosis. Distinction between seminoma and embryonal carcinoma. Cancer 1984; 54:843-8

5 Miettinen M, Virtanen I,Talerman A. Intermediate filament proteins in human testis and testicular germ-cell tumors. Am J Pathol 1985; 120:402-10

6 Eglen DE,Ulbright TM. The differential diagnosis of yolk sac tumor and seminoma. Usefulness of cytokeratin, alpha-fetoprotein, and alpha-1-antitrypsin immunoperoxidase reactions. Am J Clin Pathol 1987; 88:328-32

7 Niehans GA, Manivel JC, Copland GT, et al. Immunohistochemistry of germ cell and trophoblastic neoplasms. Cancer 1988; 62:1113-23

8 Fogel M, Lifschitz-Mercer B, Moll R, et al. Heterogeneity of intermediate filament expression in human testicular seminomas. Differentiation 1990; 45:242-9

 

This page last revised 21.5.2008.

©SMUHT/PW Bishop